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dutas
Dutasteride, marketed under brand names like Avodart and more recently in generic formulations, represents one of the most potent 5-alpha reductase inhibitors available in clinical practice. As a synthetic 4-azasteroid compound, it works by inhibiting both type 1 and type 2 isoforms of the 5-alpha reductase enzyme, which converts testosterone to the more potent androgen dihydrotestosterone (DHT). This dual inhibition mechanism gives dutasteride a distinct pharmacological advantage over single-isoenzyme inhibitors, particularly in conditions where DHT plays a central pathophysiological role.
avodart
Dutasteride, marketed as Avodart, represents one of the more interesting developments in urological pharmacotherapy over the past two decades. As a 5α-reductase inhibitor, it occupies a unique position in managing benign prostatic hyperplasia, though its applications have expanded beyond initial indications. What’s particularly fascinating is how this molecule differs from its predecessor finasteride in both mechanism and clinical effect. Avodart: Effective BPH Management Through Dual Enzyme Inhibition - Evidence-Based Review 1.
Finpecia: Clinically Proven Hair Regrowth for Male Pattern Baldness - Evidence-Based Review
Finpecia is the trade name for a pharmaceutical preparation containing finasteride 1mg, a synthetic 4-azasteroid compound that functions as a competitive and specific inhibitor of Type II 5α-reductase. This enzyme converts testosterone to the more potent androgen dihydrotestosterone (DHT) in various tissues, including the scalp and prostate. By inhibiting this conversion, Finpecia reduces serum and scalp DHT concentrations, which is the primary pathophysiological mechanism underlying androgenetic alopecia in genetically predisposed individuals.
Flomax: Effective Symptom Relief for Benign Prostatic Hyperplasia - Evidence-Based Review
Flomax, known generically as tamsulosin hydrochloride, is a selective alpha-1 adrenergic receptor blocker specifically formulated for the management of urinary symptoms associated with benign prostatic hyperplasia (BPH). It works by relaxing the smooth muscle in the prostate and bladder neck, which improves urine flow and reduces symptoms like hesitancy, weak stream, and nocturia. Unlike non-selective alpha-blockers, Flomax targets primarily the alpha-1A receptors found in the prostate, which minimizes effects on blood pressure—a key advancement in urological pharmacotherapy.
Hytrin: Effective Blood Pressure and BPH Management - Evidence-Based Review
Terazosin hydrochloride - that’s the real name behind Hytrin, though most of us just call it by its brand name. It’s one of those alpha-blockers that’s been around long enough that we really understand how it works in the body. Originally developed for hypertension, we found it had this interesting side effect of relaxing smooth muscle in the prostate, which made it quite useful for urinary symptoms in BPH. The way it selectively blocks alpha-1 adrenergic receptors in vascular smooth muscle and the prostate is actually quite elegant when you think about it.
minoxytop
In the landscape of hair restoration, minoxytop represents a topical 5% minoxidil solution enhanced with penetration boosters like azelaic acid and adenosine, designed for androgenetic alopecia. It’s not just another OTC option—it’s a targeted medical device that bridges prescription efficacy with at-home convenience. We initially struggled with stabilizing the formula; our first prototype caused significant scalp irritation in early user trials, which set us back nearly six months. I remember our lead chemist arguing for higher propylene glycol content to improve solubility, while the dermatology lead pushed for a gentler base—eventually, we settled on a water-ethanol vehicle with just enough penetration enhancers to maintain efficacy without compromising tolerability.
propecia
Finasteride, commonly known by its brand name Propecia when prescribed for androgenetic alopecia, represents one of the most clinically substantiated pharmacological interventions for male pattern hair loss. This 5α-reductase inhibitor fundamentally alters the hormonal landscape at the follicular level, specifically targeting the conversion of testosterone to dihydrotestosterone (DHT). The therapeutic premise is elegant in its specificity—by reducing scalp DHT concentrations, it halts the miniaturization of susceptible hair follicles, thereby preventing further hair loss and, in a significant proportion of men, promoting regrowth.
proscar
Proscar, known generically as finasteride, is a 5-alpha-reductase inhibitor medication originally developed and approved for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men. It works by blocking the conversion of testosterone to dihydrotestosterone (DHT), the primary androgen responsible for prostate growth and male pattern hair loss. Available in 5 mg tablets, it’s one of those drugs that fundamentally changed our approach to managing BPH—moving us away from purely surgical interventions toward medical management.
Proscare: Comprehensive Prostate Support for BPH Management - Evidence-Based Review
In the landscape of modern urological health supplements, Proscare represents a sophisticated multi-component formulation specifically engineered to address the complex pathophysiology of benign prostatic hyperplasia (BPH). Unlike single-ingredient supplements that often provide limited symptomatic relief, Proscare combines clinically studied botanicals with targeted micronutrients to work through multiple synergistic pathways—from reducing 5-alpha-reductase activity to modulating inflammatory prostaglandins. What’s fascinating is how this formulation evolved from our clinical frustrations with saw palmetto monotherapy, where about 40% of patients showed inadequate response despite proper dosing.