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Synonyms | |||
More info:
lopid
Gemfibrozil, marketed under the brand name Lopid, represents a significant class of lipid-modifying agents known as fibrates. Initially approved by the FDA in the early 1980s, this medication has carved out a specific niche in managing certain dyslipidemias, particularly those characterized by high triglycerides and low HDL cholesterol. Unlike statins which primarily target LDL, Lopid works through a different pathway—activating PPAR-alpha receptors to modulate lipid metabolism. What’s fascinating is how this mechanism creates both opportunities and limitations in clinical practice.
Abana: Comprehensive Cardiovascular Support Through Ayurvedic Medicine - Evidence-Based Review
Product Description: Abana is an Ayurvedic herbal formulation primarily used in cardiovascular health management. It’s one of those interesting supplements that bridges traditional medicine and modern cardiology practice - we’ve been using it in our integrative cardiology clinic for about 15 years now, and the results have been… well, let’s just say more nuanced than the marketing materials suggest. 1. Introduction: What is Abana? Its Role in Modern Medicine When patients first ask me “what is Abana,” I usually start by explaining it’s not a single herb but rather a sophisticated polyherbal formulation that’s been used in Ayurvedic medicine for centuries.
Aciphex: Effective Acid Reduction for GERD and Ulcer Healing - Evidence-Based Review
Product Description Let me walk you through what we’re actually dealing with here. Aciphex isn’t your typical over-the-counter supplement - it’s a prescription proton pump inhibitor (PPI) containing rabeprazole sodium. We’re talking about a delayed-release tablet that works by irreversibly blocking the H+/K+ ATPase enzyme system (the proton pump) at the secretory surface of gastric parietal cells. Essentially, it shuts down acid production at the final step. The formulation is clever - enteric-coated to survive stomach acid and release in the intestine where absorption happens.
aggrenox
Aggrenox is a combination medication containing 200mg of extended-release dipyridamole and 25mg of aspirin, specifically formulated for secondary stroke prevention. It represents one of the most rigorously studied antiplatelet regimens in cerebrovascular medicine, with a unique dual-mechanism approach that sets it apart from single-agent antiplatelet therapies. 1. Introduction: What is Aggrenox? Its Role in Modern Medicine When we’re talking about secondary stroke prevention, Aggrenox occupies a unique space that many clinicians don’t fully appreciate until they’ve worked with it extensively.
bupron sr
Bupropion SR, or sustained-release bupropion, represents one of those rare psychopharmacological innovations that actually changed how we approach depression treatment in clinical practice. Unlike the flood of me-too SSRIs that dominated the 90s, bupropion brought something genuinely different to the table - a novel mechanism that didn’t involve serotonin, which was revolutionary at the time. I remember when we first started using it at our clinic, we had this mixture of skepticism and excitement because here was something that finally addressed depression without the sexual side effects that plagued so many of our patients on traditional antidepressants.
contrave
Contrave represents one of the more interesting pharmacological approaches to weight management we’ve seen in recent years—it’s not another stimulant-based appetite suppressant or surgical intervention, but rather a combination therapy targeting the neurological pathways involved in craving and satiety. When I first reviewed the clinical trial data back in 2014, I was skeptical about combining bupropion and naltrexone—two established medications with completely different primary indications—for chronic weight management. But the neurobiological rationale actually holds up surprisingly well in practice.
Dipyridamole: Comprehensive Thrombosis Prevention and Cardiovascular Protection - Evidence-Based Review
Dipyridamole is an intriguing pharmaceutical agent that occupies a unique niche in cardiovascular medicine. Initially developed as a coronary vasodilator in the 1950s, this platelet aggregation inhibitor has demonstrated surprising versatility across multiple clinical domains. What began as an antianginal medication has evolved into a crucial tool for stroke prevention, cardiac stress testing, and even experimental antiviral applications. The compound’s complex mechanism—simultaneously inhibiting platelet phosphodiesterase and adenosine deamination—creates a fascinating pharmacological profile that continues to reveal new therapeutic possibilities decades after its discovery.
Eliquis: Advanced Stroke Prevention in Atrial Fibrillation - Evidence-Based Review
Apixaban, marketed under the brand name Eliquis, represents a significant advancement in anticoagulation therapy. This direct oral anticoagulant (DOAC) selectively inhibits Factor Xa in the coagulation cascade, offering predictable pharmacokinetics without requiring routine monitoring. Developed through collaboration between Bristol-Myers Squibb and Pfizer, Eliquis has transformed the management of thromboembolic disorders since its initial FDA approval in 2012. Unlike traditional vitamin K antagonists like warfarin, Eliquis demonstrates fewer food and drug interactions while maintaining robust efficacy in stroke prevention, venous thromboembolism treatment, and postoperative thromboprophylaxis.
Haridra: Comprehensive Anti-Inflammatory and Antioxidant Support - Evidence-Based Review
Product Description: Haridra, derived from the rhizome of Curcuma longa (turmeric), represents one of the most extensively researched herbal supplements in modern integrative medicine. Unlike standard turmeric powder used in cooking, therapeutic-grade haridra preparations are standardized for curcuminoid content and often enhanced with bioavailability agents to overcome poor absorption. The clinical interest stems from its multimodal mechanism of action, primarily through nuclear factor-kappa B (NF-κB) inhibition and Nrf2 pathway activation, giving it both anti-inflammatory and antioxidant properties.
